Paclitaxel in Combination with Coumarin as a Potentially Effective Anticancer Agent
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چکیده
منابع مشابه
Interaction of the anticancer agent Taxol (paclitaxel) with phospholipid bilayers.
Taxol (paclitaxel), a promising agent for use in ovarian and breast cancer, was incorporated into lipid vesicles (liposomes) composed of different saturated and unsaturated phosphatidylcholines, as well as saturated phosphatidylcholines mixed with the anionic phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphatidylserine (DMPS) at different molar ratios, to yield information about Taxol-liposome ...
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Paclitaxel (PTX), introduced into the clinic in 1991, has revealed itself as an effective antimicrotubule drug for treatment of a range of otherwise intractable cancers. Along with docetaxel (DTX) and in combination with other agents such as cisplatin, it has proven to be a first-line therapy. Unfortunately, PTX and DTX carry severe liabilities such as debilitating side effects, rapid onset of ...
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ژورنال
عنوان ژورنال: Pharmaceutical Biology
سال: 2000
ISSN: 1388-0209,1744-5116
DOI: 10.1076/1388-0209(200007)3831-sft192